Plant Derived Supplements – STG Makise Lifeup USA

Pumpkin Seed Oil & JIPANG Ginger set

CustomerTeam — Fri, 10 Dec 2021 01:55:03 +0000

Rich in vitamins, minerals, and antioxidants, pumpkin is highly nutrient-dense and incredibly healthy food. The tribal populace of Native America, including the Aztec cultures (1300 to 1500 AD), has used pumpkin and its seeds for food and medicinal purposes. The United States pharmacopeia has listed pumpkin seeds as an effective medicine for treating parasites. These seeds have existed in traditional and alternative therapeutic practices for treating gastric disorders, urinary illnesses, prostate problems, tapeworms, and intestinal parasites.

Even today, pumpkins, their seeds, and seed oils are used as wholesome food by people as an essential part of everyday cooking across the world.

We use pumpkin seed oil from Austria, which is eco-friendly and native to scenic Styria.

Shell Ginger (Alpinia zerumbet) is a tropical perennial plant with wonderful preventive effects. JIPANG Ginger Optimal is packed with wholesome nutrients, making it the best complimentary supplement with the Pumpkin Seed Oil. It can create a mutual supplementation effect and provide relief to Benign prostatic hyperplasia with several other health benefits.

The combination of Pumpkin seed oil and JIPANG Ginger Optimal is very effective for BPH, frequent urination, increased urinary urgency, and maintaining overall health.

Cucurbita pepo (Pumpkin seed oil)

Cucurbita pepo, commonly referred to as acorn squash, is a sprawling vine with yellow fruit-bearing flowers belonging to the family of Cucurbitaceae. It is grown primarily as a vegetable or ornamental plant.

Pumpkin seeds are nutritious, flat, oval-shaped seeds with a sweet and nutty flavor. They may be small but are powerhouses of nutrients. They are popularly known as ‘Pepitas’ in America.
The oil extracted from the pumpkin seeds is also called pepita oil. It contains a good range of nutrients, including essential fatty acids (EFAs), antioxidants, iron, calcium, B2, folate, copper, iron, manganese, magnesium, potassium, and plant sterols.

Pumpkin seed oil, a potent supplement for the Prostate

Benign prostatic hyperplasia (BPH), also known as prostate gland enlargement, is a condition in men characterized by enlarged or inflamed prostates. It is a non-cancerous prostate. It occurs due to the non-malignant proliferation of epithelial prostate cells and smooth muscle cells.

The symptoms of BPH begin when the tissues overgrow around the urethra, making its opening constrict. It causes problems with incomplete urination, frequency, urgency, nocturia, and decreased urine flow. Even though it is non-cancerous, BPH requires prompt medical attention.

Pumpkin seed oil relaxes bladder smooth muscle and increases urination. The mechanism behind this is the suppression of the α1-adenosine receptor involved in the bladder micturition reflex.

Effects of zinc

Zinc is critical to normal prostate function. The zinc concentration in the prostate is higher than that of any other soft tissue in the body, making zinc significant to normal prostate function. The data from a 2011 study showed that men with BPH had significantly less zinc than normal prostate tissue. The study also identified an increase in urinary zinc excretion.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114577/

The pumpkin seed oil is rich in zinc. This oil support prostate health and aid in decreasing the size of the prostate. It is also effective for improving maximal urinary flow rate.

Effects of phytochemicals

The presence of cucurbitacin, a chemical component in pumpkin seeds, has been found to be effective for BPH. Two isozymes of 5α-reductase produce dihydrotestosterone. The pumpkin seed oil has an inhibitory effect on 5-α-reductase. Cucurbitacin blocks the conversion of testosterone (male hormone) into dihydrotestosterone (an associated element) which promotes the formation of prostate cells.

Like saw palmetto extract, pumpkin seed oil also has an inhibitory effect on 5-α-reductase and prevents BPH. Another enzyme called aromatase metabolizes testosterone to estrogen called 17-β-Estradiol (E2). It has a powerful estrogen function that thickens and enlarges prostate tissue. The pumpkin seed oil also has an aromatase inhibitory effect.

In particular, pumpkin seed oil relaxes bladder smooth muscle and increases urine output via the α1 adenosine receptor involved in the bladder micturition reflex. This process hence reduces frequent urination and increased urinary urgency.

What the study says

A one-year study in over 1,400 Korean men with BPH found that pumpkin seed oil can be an effective alternative medicine with no adverse reactions. Participants in the study had improvement in symptoms, including better urinary flow.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809240/

Also, in 2014, researchers found that pumpkin seed oil might help treat urinary disorders in men and women. The use of the oil led to a reduction in symptoms of an overactive bladder.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032845/

The role of Cucurbita pepo in the management of patients affected by lower urinary tract symptoms due to benign prostatic hyperplasia: A narrative review:
https://www.ncbi.nlm.nih.gov/pubmed/27377091

Inhibition of the experimental induction of benign prostatic hyperplasia: a possible role for fluted pumpkin (Telfairia occidentalis Hook f.) seeds.
https://www.ncbi.nlm.nih.gov/pubmed/21709398

Other health benefits of pumpkin seed oil

Cardio-protective
Pumpkin seeds contain omega-3 and omega-6 fatty acids, antioxidants, and fiber, beneficial for heart health. The fiber in pumpkin seeds helps lower the total amount of cholesterol in the blood and decrease the risk of heart disease. Magnesium in pumpkin seeds helps to lower our blood pressure.

Menopausal Symptoms
Pumpkin seed oil can relieve some of the symptoms of menopause. This included a decrease in hot flashes, joint pain, and headaches.

Prevention from Cancer
Diets rich in pumpkin seeds and the use of pumpkin seed oil may reduce the risk of stomach, breast, lung, prostate, and colon cancers.

Helps in the management of metabolic diseases
Pumpkin seed oil can help maintain glycemic control and manage the blood sugar level. The high magnesium content of pumpkin seeds may be responsible for its positive effect on diabetes. The antioxidants present in the pumpkin seed oil neutralize the reactive oxygen species (ROS) that play a role in the development of diabetes.

Hair growth
Pumpkin seed oil is beneficial for hair treatment, especially in men with androgenetic alopecia.

Skin health
Pumpkin seed oil is a good source of squalene, an antioxidant similar to beta carotene that protects the skin from UV rays. It also prevents infections and keeps skin acne-free.

Boosts the immune system
The pumpkin seed oil has a high vitamin E content and other antioxidants. It helps to strengthen the immune system and maintain healthy blood vessels.

Helps with insomnia
Pumpkin seed oil is a source of tryptophan, an amino acid that can help promote sleep. The zinc in these seeds can also help convert tryptophan to serotonin, which converts into melatonin that regulates your sleep cycle.

Alleviates mental stress
Magnesium in pumpkin seeds helps to reduce stress and anxiety

JIPANG Ginger Optimal and Pumpkin Seed Oil for an effective prostate health

JIPANG Ginger Optimal® is a plant-derived shell ginger supplement with added Ferulic Acid, Vitamin D3, and Vitamin A. For hundreds of years, the benefits of Shell Ginger have markedly endowed to the health and longevity of Okinawan people.

It is rich in polyphenols, dietary fibers, and carotenoids. It contains 34 times more polyphenols than red wine. Polyphenols are excellent antioxidants that protect the body from damage caused by harmful molecules called free radicals. Due to such high polyphenol content, JIPANG Ginger Optimal is beneficial for prostate problems.

Moreover, ferulic acid and other polyphenols have an anti-inflammatory and antioxidant effect and protect the body from fatal conditions like cancer and cardiovascular diseases. Vitamin A and Vitamin D provide a boost to your immune system by promoting antibodies production.

For the cure of BPH, the combination of JIPANG Ginger Optimal and Pumpkin seed oil is the best and effective choice in healing symptoms and nourishing wellness.

Pumpkin seed oil is a powerhouse of nutrients with various health effects. Studies have shown promising shreds of evidence of its benefits to Benign prostatic hyperplasia. The combination of Pumpkin seed oil and JIPANG Ginger Optimal can be best for BPH due to the mutual supplementation effect.

The post Pumpkin Seed Oil & JIPANG Ginger set appeared first on STG Makise Lifeup USA.

Red Vine Leaf – Healthy Vein Circulation 60 capsules (30 capsules x 2 packets)

CustomerTeam — Wed, 27 Jan 2021 03:37:29 +0000

Manufactured in the Swiss highlands, our supplement Red Vine Leaf extract is a lot more than just an ordinary powder of grape leaves. Rich in polyphenols such as Anthocyanins and Resveratol, our supplement not only alleviates conditions such as swelling legs (edema), joint pain, and varicose veins, but also:

Increase visual awareness
Reduce blood pressure
Help provide symptomatic relief of Chronic Venous Insufficiency (CVI)
Restrict tumor formation
Prevent diabetes
Improve cognitive and motor functions

Unlike other similar products, our Red Vine Leaf supplement is exceptionally made from a proportionate amount of polyphenols. Each capsule contains an equal amount of polyphenol powder on each capsule. This means every capsule is as much effective as every other capsule. This is rarely the case with other similar products.

Vitis vinifera, the common grapevine

Vitis vinifera, the common grapevine, is a sarmentose, potent, high-powered shrub with climbing stems. It has been documented for its application in winemaking more than 3,500 years ago. The production of grapes is recognized as commercially significant, primarily related to wine production, juices, raisins, and other food products. In addition to their lucrative potential, grapes and their byproducts exhibit nutritional and functional properties.

There is a saying in Germany that goes, ‘Healthy veins and legs are like the daughter of a winery!’ (GusundeVenen un. Schoene Beinen wie ein Winzer). Also, in Italy, it has been long said that ‘Good wine makes good blood!’ (Buon vino fa buon sangue). In Indian Medicine, the grape is used for headache, dysuria, scabies, skin disease, gonorrhea, hemorrhoids, and vomiting [PDR for herbal Medicines 2004]. Over the centuries, red vines have been known for therapeutic purposes and in treating conditions like diarrhea, skin disorders, bleeding, hemorrhoids, varicose veins, and other circulatory diseases.

The alchemy behind Red Vine Leaf extract

Our Red Vine Leaf extract is magical, but the polyphenols it contains: Anthocyanins and Resveratrol, are even more so. The quantitative components of the extract are:

Polyphenols 30% or more
Anthocyanins 0.40 to 1.60%
Trans-Resveratrol 5-30 mg / 100 g (HPLC)

A type of flavonoid, Anthocyanin, is a life-saver when it comes to heart health. By improving blood sugar and cholesterol levels, it takes care of your heart with all the protection it needs. Adding to that, it has been reported to lower blood pressure by a statistically significant number.

On a more micro-level the benefits of polyphenol are countless. Starting from improved visual awareness Anthocyanin improves motor functions, prevents diabetes, restricts the growth of tumors, and prevents obesity. Similarly, it is also antibacterial and anti-inflammatory in nature, which prevents diseases by inhibiting the growth of microorganisms.

One study conducted in 2010 even concluded that Anthocyanin might help in the prevention of breast cancer. Although there’s more research to be done, it shows how promising the polyphenol could be on our overall well-being.

Another polyphenol, Resveratrol, is on a different level altogether. Studies show that it prevents Alzheimer’s by preventing the damage of nerve cells and by reducing the buildup of plaques in the brain. However, its influences extend beyond that. It has also been known to prevent heart attack and stroke by inhibiting the formation of clots and prevent cancer by restricting the growth of cancer cells.

How Red Vine Leaf Heals Your Varicose Veins and Helps Prevent Edema?

As mentioned, the Red Vine Leaf contains polyphenolic derivatives, namely anthocyanins, leuco-anthocyanins, and flavonoids. Due to the presence of such natural antioxidants, vine leaves inhibit pro‐oxidant enzymes, reduce platelet aggregation, promote vasodilation, and decrease the resistance to blood flow. They help to improve circulation and reduce the feeling of tired and heavy legs likewise.

Red Vine Leaf extract maintains the endothelial lining of tiny capillaries, promotes their repair, and reduces permeability. This reduces the leaking of fluids into the tissues during blood circulation. As a result, the swelling of surrounding tissues (edema) does not occur.

It lowers low-density lipoprotein (LDL or bad cholesterol) levels and relaxes the blood vessels. Similarly, it protects and repairs vascular endothelial cells, suppresses plaque formation, and prevents cardiovascular diseases. It also helps to draw tissue together, supporting the arrest of bleeding and diarrhea. These synergistic actions also aid in the cure of varicose veins as well as in the reduction of conditions such as painful and heavy legs.

These extracts have been shown to:

Improve lower leg blood flow
Help reduce swelling (lower leg edema)
Help provide symptomatic relief of CVI
Helps ease problems related to poor circulation.
Lessens feelings of tiredness & heaviness in legs.

Human clinical trial in Japan: Effect of Red Vine leaves on reducing the swelling of lower legs.

In a placebo-controlled clinical study conducted in Japan, a few researchers tested the effect of Red Vine Leaf powder on 17 middle-aged, healthy women. The women, who were painfully aware of their swelling legs, were given 3 capsules (600mg) of Red Vine Leaf every day after breakfast. In contrast to that, the placebo group was given 250mg of filler capsules.

After six weeks, the research found something drastic. Compared to the placebo group, the participants’ swelling was reduced by a whopping 4 times (56%). Not only that, but the researchers found no side-effects of the supplement whatsoever.

The amount of dried red vine leaf powder in the capsules used in this test was 200 mg and the human clinical intake was 600 mg of 3 capsules daily. However, our capsule contains 225 mg of Red Vine Leaf dry powder, which indicates 2 capsules are 450mg and 3 capsules are 675mg.

Please take 2-3 capsules per day for better results.

Many patients encountering varicose veins don’t often consult a doctor right away, as they’re easy to forget when they aren’t painful. But in reality, varicose veins generally get more critical over time and can lead to serious health risks. Many people who don’t treat their vein disease will experience signs of pain, fatigue, and swelling of the legs or ankles. More advanced medical complexities include hyperpigmentation, venous leg ulcers, spontaneous bleeding, superficial thrombophlebitis, and a likely life-threatening condition termed deep vein thrombosis. It can also lead to the impairment of capabilities like running and walking normally.

However, the harm caused by untreated CVI and Varicose veins is preventable. This is even true if you make certain lifestyle modifications to control them and manage your pain. Red Vine Leaf alleviates the symptoms and provides effective relief by improving the blood flow in the lower legs, reducing the swelling, and keeping your legs and veins healthy.

What’s even more, our Red Vine Leaf extract, the beneficiary antioxidants, and constantized polyphenols boost the overall functioning and maintenance of the body, thereby making them more effective than other similar supplements.

Supplement Facts

Serving size: 2 capsules
Servings per container: 30

Red vine leaf dried extract: 450 mg

Other Ingredients
HPMC(Vegetable capsule), Crystalline cellulose, Gum arabic, Sucrose fatty acid ester, Coloring (Titanium dioxide)

Package Quantity
60 capsules (30 capsules x 2 packets)

Suggested Use
2 to 3 capsules per day, or as directed by your qualified healthcare professional.

Caution
⁃ Consult with a licensed physician, pharmacist, naturopath, or other qualified healthcare professional prior to taking dietary supplements.
⁃ Consult your healthcare practitioner if you are under the age of 18, have a medical condition, or are pregnant, lactating, or trying to conceive. Keep out of the reach of children. Store tightly closed in a cool place, dry place.

The post Red Vine Leaf – Healthy Vein Circulation 60 capsules (30 capsules x 2 packets) appeared first on STG Makise Lifeup USA.

Mango Leaves – The Next-Gen Caffeine Replacement 30 capsules (15 capsules x 2 packets)

CustomerTeam — Thu, 14 Jan 2021 00:47:33 +0000

You don’t need to have caffeine anymore!

It’s no surprise that most of us are dependent upon the world’s most used psychoactive substance, caffeine. In the form of tea, coffee, sodas, and energy drinks, we use caffeine extensively to overcome stress, fatigue, and to boost focus and mental energy. Americans alone consume 400 million cups of coffee every single day. Adding to that, caffeine has even gained ground into other ‘functional foods’ like protein powders and peanut butter. Having said that, not everyone reacts well to caffeine or can handle the ever-increasing doses that are working their way into dietary supplements and energy drinks.

Although caffeine may improve performance during prolonged exercise and sports activities, its capacity to enhance power and strength is questionable. Excessive amounts of caffeine can lead to negative side effects, including rapid heart rate, frequent urination, increased blood pressure, jitters, and anxiety – due to its large effect on the cardiovascular system. Its addictive nature makes it challenging to quit caffeine as one might develop various symptoms along the process.

Mango leaf (Zynamite®), an extract from Mangifera indica, presents a synergist, natural alternative for caffeine. It enhances cognitive functions including, concentration, attention, and reaction time in healthy younger adults, with a broader range of cognitive activities than caffeine. It is a caffeine-free energy booster and improves physical and mental performance without any negative side effects.

19.4% Higher Peak Power

50 ms Faster Reaction Time

6 Clinical Trials

Made In Japan. High Quality.

What actually is Mango Leaf ?

Mango leaf (Zynamite®) is Nektium’s patent-pending proprietary Mangifera indica extract standardized to ≥ 60% mangiferin. It is a unique and natural mango tree (leaf) extract. To date, Zynamite®has been the subject of 6 clinical studies and is considered to be a potent nootropic (substances that can enhance brain performance or focus) and energy booster.

Along with its aforementioned functions, Mangifericin has other advantages on our body as well. Some of them are:

Mangiferin has anti-inflammatory, anti-microbial, anti-allergic, antihyperlipidemic, hepatoprotective, immunomodulatory, and neuroprotective properties.
Research suggests that mangiferin may reduce blood glucose levels by inhibiting glucose absorption from the intestine. This supports a healthy blood glucose level.
Mangiferin can cross the blood-brain barrier and has neuroprotective benefits such as reducing oxidative stress.

The principal active compound in Mangifera indica is Mangiferin, which is found in its leaves, bark, fruit, and roots. It has strong antioxidant, antidiabetic, hypotensive, anti-lipid peroxidation, immunomodulatory, cardiotonic, wound healing, and anti-degenerative properties. Mangiferin can even cross the blood-brain barrier and manipulate various channels and neurotransmitters in the body. Looking at the historical background, mango leaves have long been used for ailments in traditional practices.

The key features of Mango leaf include:

Rapid onset of mental activation
Faster reaction time
Sustained energy
Increased power and performance
Reduced pain and accelerated recovery
Suitable as a caffeine replacement
Supports mood, energy, and focus
Jitter-free extract for a natural source of energy
No adverse effect

What makes Mango Leaf supplement the ‘right choice’ ?

Due to its antiseptic, anti-parasitic, tonic, diuretic, and laxative properties, mango leaves have been known for centuries in Ayurveda. Mangiferin can even cross the blood-brain barrier and manipulate various channels and neurotransmitters in the body.

Although Mango Leaf supplements have multiple benefits, as mentioned before, it has mainly three prime functions:

1) Mango Leaf strengthens sports performance.

Sportsperson and athletes require sustained physical strength with intense focus and concentration. They need to have high endurance, stamina, and focus. Due to the fashion of using caffeine in energy drinks and protein powders, caffeine intake is increasing unnecessarily. This subsequently exerts negative effects on the cardiovascular system, such as rapid heartbeat, palpitations, and increased blood pressure.

In several of the sports studies conducted, cycle ergometer sprints were performed, during which peak and mean power output were analyzed. In a fatigue study, peak power was increased by 12.5% using Mango leaf. In subjects experiencing simulated exhaustion, peak power was increased by 19.4%. It provides support for the brain and body.

The results demonstrated increased peak power output, mean power output, increased VO2 max, increased brain oxygenation in women, and muscle oxygen extraction, along with decreased blood lactate concentration. This makes Mango Leaf the best choice among athletes and holds a remarkable position in sports.

2) Mango Leaf increases mental energy and cognitive functions.

Heavy mental activity, stress, or fatigue makes people lack enthusiasm and makes them desperate and exhausted. In such conditions, people desire a boost of energy that enhances physical performance, attention, concentration, alertness, and mental state. This is why many people are dependent upon caffeine and eventually become addicted to it. Caffeine-addiction consequently brings adverse side effects, which don’t exist with Mango leaf.

One of the clinical studies done with Mango leaf in finding cognitive support observed that standard reaction time (SRT) was decreased by 50 milliseconds. Clinical studies of formulations containing Zynamite point to rapid onset of enhanced brain electrical activity, with statistically significant improvement in reaction time and calculation performance.

Mango Leaf supplementation can raise your focus level, reaction time, including calculation performance. These features are extremely crucial in sports activity and dealing with stress and energy deprivation.

3) Mango Leaf decreases muscle damage, pain, and increases sport recovery.

Likewise, energy supplementation during sports activity is not sufficient – the energy provided must sustain. Drained energy, muscle pain, fatigue, and exhaustion decrease sports performance. Mango Leaf has shown promising results in increasing muscle recovery, stamina, and performance.

The impact on pain and recovery was examined after a 10km race accompanied by 100 drop jumps. The results showed an accelerated recovery of muscle performance and reduced pain and muscle damage caused by competitive exercise.

More remarkably benefits of Mango Leaf

Mango leaf has a remarkably analogous effect as caffeine in stimulating the brain waves and improving Long Term Potentiation. While caffeine boosts feelings of energy, mood, and alertness via antagonism of adenosine receptors, Mango leaf acts non-selectively to modulate various CNS targets and stimulate brain activity. Consequently, it does not have any adverse side effects such as caffeine.

Mango leaf supplement improves performance, brain oxygenation, peak power and VO2 max, giving all athletes and active health enthusiasts sustained clean energy to push forward without fatigue. In a world dependent upon caffeine, Mango leaf could be a healthy substitute. For high-performance athletics, faster reactions and quicker adaptation to alternating conditions are fundamental and essential. The cognitive and physical advantages of Mango leaf makes it a unique solution for athletes, e-sports, shift workers, truck drivers, and every person in need of mental and physical energy.

The post Mango Leaves – The Next-Gen Caffeine Replacement 30 capsules (15 capsules x 2 packets) appeared first on STG Makise Lifeup USA.

JIPANG Ginger Powder (60g) – Powder

CustomerTeam — Wed, 10 Jun 2020 05:29:51 +0000

Shell ginger (Alpinia zerumbet is the botanical name) is a tropical perennial plant that grows in abundance in Okinawa and continues to be used in traditional Okinawan cuisine and as a traditional remedy. The leaves of shell ginger come in two forms – deep green and gold striped. It blooms amazing yellow flowers around July and white blossoms in early summer. Shell ginger has a long and respected history.

You may not be familiar with the plant called “Shell Ginger” (Alpinia zerumbet). Shell ginger is different from ordinary ginger. Please don’t confuse shell ginger with ordinary one. Very much different in health benefits. Because it grows in Okinawa’s subtropical climate, it has thousands of phytochemicals that protect itself from strong sunlight.

For 12 years, we have been producing health supplements from this plant. Our brand name is “JIPANG Ginger” which helps thousands of people to maintain and improve their health and vitality not only in Japan but also all over the world. And recently, we started to offer two kinds of JIPANG Ginger.

Shell Ginger leaves fermented into powder (Capsule type) – more info>>
Simple powder of shell ginger leaves (Powder Type)

Does Shell Ginger Promote Longevity?

With a life expectancy of 84.55 years in 2019, Japan always on the top list when it comes longest life expectancy. Many longest-living people of Japan are from Okinawa where many residents are over 100 years old. Among the many reasons contributing to their longevity, nutrition and the “Okinawan diet” are said to be key elements for highest life expectancy and healthy lives in Okinawa

So what exactly makes the Okinawan diet special?

One local ingredient, called shell ginger(Alpinia zerumbet), has become the focus of different studies and can be said to be a substantial contributor to longevity in Okinawa. Shell ginger has been used for various purposes in the lives of people living in Okinawa. Leaves of shell ginger have long been used as packing materials for rice cakes (Mochi) and custom to eat it to pray for good health.

Okinawa Mochi Wrapped in Shell Ginger leaves

High in Antioxidants

JIPANG Ginger has outstanding antioxidant properties. Antioxidants act as “shields” for our bodies from free radicals. Antioxidants help us fight the free radicals that cause aging. Free radicals are one of the reason we age, and they cause our bodies to burn through energy faster and slow down our metabolism.

It is thought that free radicals can attack the cells in our body. They can cause cell damage and may also be linked to various other diseases. If you are not getting enough antioxidants in your diet, this can lead to oxidative stress, which can eventually lead to cell damage and risk of developing cancer, heart disease, and many other chronic illnesses and health problems.

Full of Healthy Polyphenols - 34 Times more Polyphenols than Red Wine

Shell ginger contains 34 times more polyphenols than red wine, which makes our JIPANG Ginger lifesaver supplement. The compounds in the polyphenols act like anti-inflammatory agents that stop the growth of inflammatory cells that cause inflammation. When the amount of polyphenols is increased, this makes the body’s inflammatory response to particle exposure much more effective. These same compounds also protect us from other health problems, like cardiovascular disease and cancer. They help keep us out of danger since they limit the growth of many of the carcinogens that are usually involved in cancer cells’ growth. This is why polyphenol intake is said to be an important component of a healthy diet.

Focusing on the traditional fermentation technique, we fermented Shell Ginger with the fungus “Aspergillus niger”. So, we discovered that some phytochemicals were significantly increased. We don’t know exactly how the many phytochemicals such as polyphenols, terpenoids, kava pyrones, phenylpropanoids, sterols, etc. are absorbed in the intestine.

For example, polyphenol here is 8000 types, and their absorption rates from the intestinal tract are all different. In general, its absorption rate is generally not high. The absorption rate of flavanol, chalcone, and isoflavone is about 5 to 30%. As the amount of these polyphenols increases due to fermentation, the amount of polyphenols in the blood also increases. So the anti-obesity, anti-oxidant, anti-glycation, anti-platelet, osteogenic, and neuraminidase inhibitory activities are enhanced.

Shell ginger also contains carotenoids. Carotenoids have a low absorption rate of 0.1% to a few%, but if you eat a lot of them, most of them will be taken into the body in proportion to the amount you eat. Although still in the research stage, some carotenoids in shell ginger are significantly increased by fermentation. Carotenoids have various health-promoting effects similar to polyphenols.

However, there should be beneficial enzymes and nutrients that are destroyed by fermentation. For example, curcumin in turmeric exhibits a liver function-improving effect. But curcumin must be metabolized to tetradehydrocurcumin by a special enzyme to exert its effect. If the enzyme is destroyed, curcumin is useless. (Please don’t worry. This enzyme is not decomposed by fermentation because it exists in the epithelial cells in the intestine. I just write an example.)

Good Sources of Dietary Fiber

Dietary fiber is a good thing for your body. It helps to prevent the buildup of toxins in your system. Without dietary fiber in the diet, you can be at risk for irritable bowel syndrome, colon cancer, dyslipidemia, constipation, obesity, diabetes, etc. Fiber will enable your body to be able to absorb the food that you eat much more easily, thereby eliminating that problem that we talked about before. Another good thing about fiber is that it allows you to feel full faster. This allows you to eat less overall and still have enough nutrients for the rest of your day.

Shell ginger powder contains as much as 60% dietary fiber. So it is a good source of dietary fiber.

Various Ways to Drink and Eat Shell Ginger

We use only Okinawa shell ginger leaves which are carefully chosen. Since shell ginger is processed to powder, then it can be mixed with Western confectionery such as cakes, ice cream, yogurt, jelly as well as other foods. Polyphenols generally do not stay long in the body after being absorbed in the intestine. At best, for 2 to a few hours. Therefore, if you want to get the best effect of polyphenols, you should take it every few hours. For that, you are encouraged to drink shell ginger tea just like coffee. Both types – fermented type and non-fermented simple type – are OK for tea.

The post JIPANG Ginger Powder (60g) – Powder appeared first on STG Makise Lifeup USA.

JIPANG Ginger Optimal – 60 Vegetable Capsules

CustomerTeam — Tue, 25 Feb 2020 01:52:52 +0000

Shell Ginger (Alpinia zerumbet) is a tropical perennial plant. Against three major modern diseases — Alzheimer’s disease, cardiovascular diseases, and cancer — Shell Ginger exerts wonderful preventive effects. Therefore this plant should be called a modern day ‘Panacea’. The Panacea /pænəˈsiːə/ is a term named after the Greek goddess of universal remedy Panakeia. In Japan for centuries it has been consumed in Okinawa whose population is frequently cited as “the healthiest on earth,” boasts an impressively low incidence of cardiovascular disease, stroke, and cancer. The scientist made a recent experiment on worms and discovered that those fed on a daily diet of Shell Ginger lived an average of 22.6 percent longer than the control group. This miraculous plant is packed with dozens of polyphenols such as Chlorogenic acid, Ferulic acid, Quercetin, Epicatechin, Catechin, and Kaempferol.

And from February 2021, we can supply you with our recent product of Shell Ginger (JIPANG Ginger Optimal®) to which Ferulic Acid, Vitamin D3, and Vitamin A are newly added.

Ferulic acid is a type of polyphenol, but it is not as well known as quercetin and catechins. Ferulic acid is thought to play an important role in strengthening brain function, improving healthy skin, reducing insulin resistance, protecting bone loss, and delaying aging. Therefore, although Shell Ginger already contains a lot of ferulic acids, we have added this very important polyphenol.

Vitamin A works to produce IgA antibody, which is responsible for local immunity to the mucous membrane that is the first defense mechanism against viruses and bacteria in the human body. IgA binds to pathogens and viruses on the surface of the mucous membrane, nullifies the toxins that the pathogens and viruses carry, and prevents them from becoming infected.

Vitamin D activates macrophage which is a type of white blood cell that is found throughout the body, including the blood, brain, liver, lungs, and intestines. It has the function of eating bacteria and viruses that have invaded the body and is one of the important immune cells that protects us from infectious diseases.

This vitamin induces the production of “cathelicidin” and “defensin”, which are expected to have bactericidal and antibacterial effects. Vitamin D is also expected to have the effect of suppressing cytokine storms. Vitamin D controls tight junction proteins, which enhance barrier function and protects the skin and intestines. About 60% of the body’s immune cells are present in the intestine, so protecting the intestine can be expected to boost the immune system.

JIPANG Ginger Optimal® is a very important supplement in this pandemic era.

So, what does shell ginger contain to be so effective against various diseases?

Polyphenols– Polyphenols are powerful antioxidants. Antioxidants protect the body from damage caused by harmful molecules called free radicals. Shell ginger contains 34 times more polyphenols than red wine, which makes our JIPANG Ginger Optimal lifesaver supplement. The compounds in the polyphenols act like anti-inflammatory agents that stop the growth of inflammatory cells that cause inflammation.

→Oxygen Radical Absorbance Capacity is a method of measuring antioxidant properties in biological samples, developed by researchers at the United States Department of Agriculture (USDA) and the National Institute on Aging in 1992. Higher the ORAC (Oxygen Radical Absorbance Capacity) value, higher is the antioxidant property of that sample. JIPANG Ginger® has outstanding antioxidant capacity compared with other foods.

→DPPH: 2,2- Diphenyl-1-picrylhydrazyl, commonly known as DPPH is a strong radical and is a visual method used to check the antioxidant property of a sample.

Chlorogenic acid– It decreases the uptake of glucose in the body and assist in regulating blood glucose levels and impacts on the reduction of lipid peroxidation, resulting in significant heart health benefits.

Ferulic acid– Ferulic acid has powerful antioxidant properties with wide-ranging functions, from anti-aging support to improved cholesterol management to cancer prevention. Its antioxidant effect on the skin is particularly impressive and is often used as an ingredient in skin care products. It has the ability to abrogate the destructive and toxic effects of beta-amyloid peptide which is the protein now believed to impair memory in Alzheimer’s disease.

Quercetin– Several laboratory studies show quercetin may have anti-inflammatory properties, and it is being investigated for a wide range of potential health benefits.

Epicatechin– has insulin mimicking action and improves heart health. Dr. Norman Hollenberg of Harvard Medical School even suggests to consider epicatechin as a vitamin.
Catechin– In laboratory tests, the catechins present in tea leaves have been shown to inhibit the growth of cancer cells. In addition to this, they are able to prevent the activity of free radicals, the molecules which cause cellular damage that can lead to cancer.
Kaempferol– is a strong antioxidant and helps to prevent oxidative damage to our cells, lipids and DNA.

Polyphenol Benefits

Most polyphenols are anti-oxidants, and being anti-oxidants they can minimize the damage done by free radicals on the body. Free radicals are often blamed for causing cellular damage which is associated with aging. Polyphenols are also known to help the immune system, and a strong immune system is important for good health. Polyphenols can also improve the circulation of blood, which can lower the risk of heart and cardiovascular disease.

Thanks to the above mentioned nutrients, fermented leaves of Shell Ginger are effective in the prevention of the following conditions.

Alzheimer’s disease is characterized by progressive loss of memory, language, reasoning and other cognitive functions, including dementia, the presence of senile plaques, neurofibrillary tangles, and synapse loss. Increased oxidative stress, decreased antioxidants, mitochondrial damage and other factors play major roles in the development and progression of Alzheimer’s disease. Shell Ginger contains key compounds, especially Ferulic acid, that have been found useful in combating Alzheimer’s disease (AD), which could mean that this supplement might be able to keep the decline from starting. Ferulic acid (FA) as an antioxidant is able to act as a free radical scavenger. Ferulic acid dose-dependently inhibits fAβ (β-Amyloid Fibrils ) formation from amyloid β-peptide. It is a β-secretase modulator with therapeutic potential against Alzheimer’s disease.
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1471-4159.2004.02899.x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517023/
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055774.
https://www.sciencedirect.com/science/article/pii/S0006291X05017821
https://www.tandfonline.com/doi/abs/10.1586/14737175.2015.955853?src=recsys&journalCode=iern20

Cardiovascular diseases (Heart Protection): Several types of research have reported effects consistent with pharmacological applications of quercetin and other polyphenols in cardiovascular diseases. Chlorogenic acid suppresses chronic ventricular remodeling after myocardial ischemia because it is critically involved in the suppression of macrophage infiltration. Another compound, epicatechin alters mitochondrial function and membrane fluidity to produce cardiac protection. Several other types of research have reported effects consistent with pharmacological applications of quercetin in cardiovascular diseases.

https://www.ncbi.nlm.nih.gov/pubmed/23774243
http://www.fasebj.org/doi/abs/10.1096/fasebj.26.1_supplement.852.1
https://www.ncbi.nlm.nih.gov/pubmed/20579545
https://www.ncbi.nlm.nih.gov/pubmed/25915608

Cancer: Shell Ginger can also be effective in the treatment of many types of cancers. It has been found that chlorogenic acid induces cell cycle arrest at the S phase and suppresses the activation of the extracellular signal-related kinase. Chlorogenic acid sensitizes hepatocellular carcinoma cells to 5-FU (Fluorouracil) treatment by the suppression of extracellular signal-regulated kinases (ERK) activation through the overproduction of ROS (Reactive Oxygen Species). Ferulic acid may be used as an effective therapeutic agent against breast cancer. Ferulic acid might inhibit proliferation and induce apoptosis via inhibiting PI3K/Akt pathway in osteosarcoma cells. In the etiology of cancer, free radical plays a major role; therefore, antioxidants present in diet have fastidious consideration as potential inhibitors of abandoned cell growth. Ferulic acid’s anti-carcinogenic activity is related to its capability of scavenging ROS and stimulation of cytoprotective enzymes. Quercetin has also been studied extensively as a chemoprevention agent in several cancer models.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415958/
https://link.springer.com/article/10.1007/s11010-017-3171-1
https://www.ncbi.nlm.nih.gov/pubmed/27177074
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846940/
https://www.sciencedirect.com/science/article/pii/S2215017X14000368
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736626/

Metabolic syndrome is a cluster of conditions such as increased blood pressure, high blood sugar, excess body fat around the waist, and low HDL or high triglyceride level which occur together, increasing your risk of heart disease, stroke, and diabetes. It has been seen that one of the polyphenols found in shell ginger, Chlorogenic acid markedly alters the increased plasma total cholesterol and low-density lipoprotein but decreases high-density lipoprotein diet with a dose-dependent improvement on both atherogenic index and cardiac risk factor. It has also shown to delay intestinal glucose absorption, inhibit gluconeogenesis and stimulates glucose transport in skeletal muscle via the activation of (AMP-activated protein kinase).

Post-menopausal syndrome: Post Menopause is the years after menopause. During this stage, menopausal symptoms, such as hot flashes, can annoy many women. As a result of a lower level of estrogen, postmenopausal women are at increased risk for a number of health conditions, such as osteoporosis and heart disease.Quercetin has also been found useful for the treatment of postmenopausal problems and effective in preventing recurrent urinary tract infections, especially if administered with vaginal estrogen therapy.
https://www.ncbi.nlm.nih.gov/pubmed/27838537

Perimenopause is also called the menopausal transition. Women start perimenopause at different ages with symptoms such as hot flashes, sleep problems, and vaginal dryness. In the early 1960s, ferulic acid was found to be effective for reducing menopausal symptoms, including hot flashes. It has been found that ferulic acid may protect against various inflammatory conditions due to its free-radical scavenging effects.
https://pdfs.semanticscholar.org/f2ed/9282e8f07d5e4968a23877884a1751fca442.pdf

Prostate problems: Shell Ginger improves immunity and re-establishes hormonal and enzymatic homeostasis or balance which helps to tackle prostate cancer. One of the compounds present in shell ginger called beta-sitosterol is also found effective against prostate cancer. Shell Ginger grown in Okinawan soil is packed with dozens of polyphenols that act synergistically to become powerful natural antioxidants with the ability to protect normal human cells. It has been found that chlorogenic acid exhibits a restraining effect on benign prostatic hyperplasia and its mechanism might be related to inhibit typeⅡ-alpha-reductase activity. Another study has shown that ferulic acid may lead to cell cycle arrest in prostate cancer cells. Epidemiologic studies have also shown a chemopreventive effect of quercetin on prostate cancer that has been exhibited in animal experiments.

Maintenance of blood glucose level: A study was carried out to investigate whether chlorogenic acids modulate glucose uptake and gastrointestinal hormone and insulin secretion in humans. It was found that chlorogenic acid might have an antagonistic effect on glucose transport. Therefore, a novel function of some dietary phenols in humans may be to attenuate intestinal glucose absorption rates and shift the site of glucose absorption to more distal parts of the intestine. It is also found that chlorogenic acid decreases the uptake of glucose in the body and assist in regulating blood glucose levels and impacts on the reduction of lipid peroxidation, resulting in significant heart health benefits. https://academic.oup.com/ajcn/article/78/4/728/4690021

Inhibition of formation of AGEs: Advanced glycation end products (AGEs) are major factors responsible for the complication of diabetes. Labdadiene is a potent antiglycation agent found in shell ginger which was found to inhibit AGEs formation in three different steps in the pathway. These data indicate that labdadiene could be used to prevent glycation-associated complications in diabetes. Another flavonol, Quercetin, found in shell ginger leaves can effectively inhibit the formation of AGEs in a dose-dependent manner via trapping reactive dicarbonyl compounds. In the bovine serum albumin (BSA)–MGO/GO system, quercetin traps Methylglyoxal (MGO) and glyoxal (GO) directly and then significantly inhibits the formation of AGEs.
https://www.sciencedirect.com/science/article/pii/S0308814611005838
https://pubs.acs.org/doi/abs/10.1021/jf504132x

Skin problems: Chronic exposure to endogenous and environmental pro-oxidant agents, leads to the generation of reactive oxygen species. Antioxidants protect the body from damage caused by harmful molecules called free radicals. The rhizome aqueous extract of Shell Ginger is a good source of bioactive compounds against enzymes responsible for causing skin diseases. Moreover, Kavalactones found in Shell Ginger could be used as a potent inhibitor and can be further exploited to be used in anti-skin disease formulations. Another compound, kaempferol has also been found as a potent chemopreventive agent against skin cancer.

Atopic dermatitis is a condition that makes your skin red and itchy. Dr. Makise has treated more than 40,000 patients suffering from atopic dermatitis, with stunning results. One reason for Shell Ginger’s success according to Dr. Makise is its detoxification effect.
https://www.ncbi.nlm.nih.gov/pubmed/22827920
https://www.sciencedirect.com/science/article/abs/pii/S0006295210004764

Psoriasis is a common skin condition that speeds up the life cycle of skin cells. Dr. Makise recommends taking JIPANG Ginger in a dose of 1400 mg-2000 mg/day as supplement therapy to prevent the relapse of psoriasis. Flavonoids present in Shell Ginger offer some protection against psoriatic complications through their roles as inhibitors of inflammation and as free radical scavengers. It has also been found that quercetin has the potential against further development as a candidate for psoriasis treatment. For more information about Psoriasis treatment click here>>

Other Ingredients
HPMC (Vegetable capsule)
Package Quantity
60 capsules
Suggested Use
2 capsules daily with or without food. If your stomach is sensitive, please take these supplements after meals or with meals.

Caution

⁃ Consult with a licensed physician, pharmacist, naturopath, or other qualified healthcare professional prior to taking dietary supplements.
⁃ Consult your healthcare practitioner if you are under the age of 18, have a medical condition, or are pregnant, lactating, or trying to conceive. Keep out of the reach of children. Store tightly closed in a cool place, dry place.

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